Clinical Pearls: Ventilator Modes 101
Briana Juskowiak Briana Juskowiak

Clinical Pearls: Ventilator Modes 101



There are a number of reasons why ventilators are confusing, and I’ll break down how to simplify these factors in this blog post. But the big takeaway is this: just because a patient seems controlled well on the vent does not mean he is; do not leave the task of interpreting the vent and the patient’s response to the vent to others. It is incumbent on you to educate yourself about what the knobs, numbers, and waveforms mean in order to better treat your patient. Let’s talk vent basics and it starts with understanding the mode.

Read More
Clinical Pearls: Is It Time To Extubate, An Objective Approach
Briana Juskowiak Briana Juskowiak

Clinical Pearls: Is It Time To Extubate, An Objective Approach



I spent a lot of years working at the bedside in the ICU. I can tell you one thing a nurse won’t tolerate and that’s an agitated and intubated patient. IYKYK. It’s scary, it’s physically taxing for you, and it’s not good for the patient. So naturally I would immediately call the provider with the “can we extubate” query when they woke up fighting. In my mind they were awake, right? Let’s liberate them from the ventilator!

This is only one scenario in which the clarity I gained in NP school blew my mind at how naive I was as a nurse. Maybe naive isn’t the right word, uninformed perhaps? IDK, I think my point is I didn’t realize there was a systematic approach to assessing extubation readiness. I didn’t properly think through all the reasons why a person would need a vent, nor appreciate all the ways in which a person can fail an extubation attempt. One key factor I learned is that objective medical analysis of the diagnosis and current exam is crucial in predicting risk and then weighing the risk/benefit ratio to determine what is safest for the patient. In this post I’ll walk you through the step by step process of performing this assessment to eliminate as much doubt as possible and set your patient up for success. Skip to the end for a bedside checklist.

Read More
Clinical Pearls: Calcium Channel Blocker Overdose
Briana Juskowiak Briana Juskowiak

Clinical Pearls: Calcium Channel Blocker Overdose



Toxic levels of calcium channel blockers typically induce massive cardiogenic and distributive shock and pressors alone often won't save them. High dose insulin therapy enters the chat here. Think 700 units of rapid onset insulin IV per hour 🤯. Yep, it's gonna be an all hands on deck kind of patient my friends. Read this article to learn about the whys, whos, and hows of CCB overdose mgt.

Read More
Clinical Pearls: Intubation Starts Here
Briana Juskowiak Briana Juskowiak

Clinical Pearls: Intubation Starts Here

Beyond practicing the technique of intubating, nurse practitioners should spend time learning to identify the patients at risk of cardiac arrest. If you can put a finger on the major risk, there are definite strategies you can employ to improve odds of success without decline. In this article, I discuss specific approaches to: GIB/vomiting, hypoxia, shock, asthma, and metabolic acidosis.

Read More
Clinical Pearls:What’s up with the lactate?
Briana Juskowiak Briana Juskowiak

Clinical Pearls:What’s up with the lactate?

In 2001 a research article was published expounding early goal directed therapy as a treatment strategy for sepsis. Key points in the article suggest that physical exam findings are subpar for directing resuscitation and that measures such as lactate, SCVO2, base deficit, and pH are more accurate measures of adequate treatment. There were certainly other factors, and the take home message was to find the source and start antibiotics early, but volume resuscitate until tissue hypoxia improves was the practical application of this research. As a result lactic acidosis has become a bad omen to be feared by all. Several guideline updates have since been published, the most recent in 2021 with weak evidence to suggest using lactate as an end-point measurement. Practically speaking though, the word is out that a high lactate = bad bad badness. I’m not saying it isn’t bad, but there are plenty of reasons why an elevated lactate alone is not the end of the world. In this post we’ll discuss causes for lactate elevation, what should be cause for alarm and what shouldn’t, and how to manage it.

Read More
Clinical Pearls: VBG vs ABG
Briana Juskowiak Briana Juskowiak

Clinical Pearls: VBG vs ABG

There is a legitimate reason why ER providers consistently order a VBG over an ABG and the ICU provider then may or may not believe the VBG choosing to tack on an ABG instead.

Many patients in the hospital require assessment of their acid base balance and oxygenation/ventilation status which is best quantified from serum arterial samples. Additionally, the ABG provides expedited lab results such as hemoglobin, potassium and other electrolytes, and lactic acid. These values are very helpful in making a rapid diagnosis and treatment plan. A venous blood gas seems to be the standard replacement for an arterial blood gas in the emergency department. It does offer some benefits, but has limitations as well which should be acknowledged.

The focus of this article is to describe the pros/cons of using a VBG as a surrogate, the exclusion criteria, and the method of converting a VBG to an ABG.

Read More
Clinical Pearls: DIC
Briana Juskowiak Briana Juskowiak

Clinical Pearls: DIC

One of the rare and weird things in medicine that combine a dramatic constellation of opposites. Caring for someone in the throes of badness from two dichotomous problems leaves one in a state of floundering. Do I treat the clotting or do I treat the bleeding? What will kill them first? It’s universally known that getting the diagnosis of disseminated intravascular coagulation is a dreaded event. DIC is a downstream complication that arises late in the game with several diagnoses that we see in the ICU, and unfortunately in our maternal population. Every time an OB calls our team to see or transfer a patient to ICU my shoulders instantly feel tense. Let’s talk about the pathophysiology behind this dreaded state and what our treatment options really are.

Read More
Clinical Pearls: Liver Failure
Briana Juskowiak Briana Juskowiak

Clinical Pearls: Liver Failure

Oh the ways the liver can fail. As a new nurse practitioner this one was hard to get down. Cardiology is generally seen as the bee all end all when it comes to keeping our bodies running, but I’d like to talk about the under appreciated liver. Hepatology is fascinating because the normal function of the liver is supremely multi-faceted. Throw in a little pathology and any number of pathways can be deranged and within those any degree of severity can be seen. From acute to chronic to acute-on-chronic, severity can run the gamut. Decompensated cirrhosis is a common killer in most ICU’s. Given how poorly understood this disease state is, I’d like to talk about the complexity, progression, prognosis, and management of liver failure in the intensive care unit.

Read More
Clinical Pearls: Pressor Selection
Briana Juskowiak Briana Juskowiak

Clinical Pearls: Pressor Selection

The foundation of critical care practice stands upon heart and lung support. As you know a multitude of problems lead to these downstream complications, but at its core what we do in the unit is handle worst case scenarios. Even for a new nurse practitioner with loads of years at the ICU bedside, pressor selection can be difficult at first. What I hear from students is “Levo, let’s just start Levo.” They say this because it has been their experience and it’s of course discussed everywhere. But when I ask them to defend the selection there can be a dearth of knowledge. Ultimately, they may be right, but I argue that as a competent provider one must have a good understanding of the pharmacodynamics of the drug AND the pathophysiology of the disorder you are treating. Why? Because while the physician/team you are practicing with currently may never question you, at some point you will need to explain your rationale. And on a baser level you need to accurately treat the problem or you could 1)chose something ineffective 2)make things worse or 3)harm the patient. Let’s talk vasopressors.

Read More
Clinical Pearls: Waveform Capnography
Nurse practitioner Briana Juskowiak Nurse practitioner Briana Juskowiak

Clinical Pearls: Waveform Capnography

End tidal carbon dioxide (ETCO2) measures exhaled carbon dioxide, it therefore reflects the efficacy with which CO2 is pumped back to the lungs (indirect measurement of cardiac output) and then exhaled (ventilation). Waveform Capnography is a continuous tracing, or waveform, of ETCO2. It is very useful when assessed as a trend.

Read More
The Best Nurse Practitioner Podcasts
nurse practitioner Briana Juskowiak nurse practitioner Briana Juskowiak

The Best Nurse Practitioner Podcasts

Are you an avid auditory learner? I’m slightly obsessed with podcasts. I tend to go on benders based on what is going on in my life. I listened exclusively to travel podcasts for eighteen months when I planned a European trip a few years ago. I have always liked to use podcasts as an adjunct to my professional education as a nurse practitioner. IMO it’s hard to utilize them exclusively just because the search functions are not as robust (there’s a lot to dig through to find one talk about a subject like normal labs, etc) and the content is long. But, once you find a quality show that addresses your specific population it’s great to listen to on a more regular basis (versus a search approach). The nuggets of wisdom you can garner from these discussions can greatly impact your practice. You may have to be willing to wait for them, but if you were going to be doing the dishes anyway, why not multi-task? In this post I will share my favorite podcasts (which are mostly ICU): what I love about them and how I use the info in my career as an ICU nurse practitioner.

Read More